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10.3390/antiox11020181 3 AshcroftT.SimpsonJ
-Luminol, an antioxidant, was found to prevent the age-related decreases in glutamate, glutathione and glutamine synthetase in DBA/2J retinas [19]
In contrast, IRP2 knockdown or treatment with the ferroptosis inhibitor Fer-1 alleviates PC-12 cell damage by downregulating p53 levels and activating the SLC7A11-ALOX12 signaling pathway ( In summary, CDC42, derived from neural stem cell-derived exosomes, as well as TIGAR, FTO, and IRP2, contribute to PD pathology by regulating iron homeostasis, ferroptosis, fatty acid metabolism, the antioxidant system, and angiogenesis
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doi: 10.1021/acscentsci.9b01063 28 LeeHZandkarimiFZhangYMeenaJKKimJZhuangLet al
