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R., Duno, M., Wibrand, F., Christensen, M

While the pro-inflammatory effect of microcrystalline UA is well-established 3,20 , there are several indications that soluble UA free of UA crystals has protective effects against inflammatory mechanisms and toxicity 50 with effects on macrophage polarisation towards the anti-inflammatory M2 phenotype 51

The applicant noted that it is concurrently seeking FDA authorization for in vitro diagnostic (IVD) use in the clinical microbiology laboratory for automated quantitative AST by minimal inhibitory concentration (MIC) of isolated colonies ( for aerobic and facultative anaerobic gram-negative Enterobacterales and non-Enterobacterales
The extant body of scholarly work indicates that these botanical supplements manifest their antidepressant properties not merely through straightforward pharmacodynamic mechanisms but rather via extensive modulation of neurochemical networks at a systemic level
[Abstract]2022 Dec 24:2022:3676685
