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Research Protocol Summary Study Protocol: 0.25 mg AOD-9604 administered intra-articularly via ultrasound guidance Frequency: Weekly injections Duration: 4-7 weeks in research studies Combination Therapy: 6 mg hyaluronic acid co-administered for enhanced effects Assessment Timeline: Significant improvements observed by 8-9 weeks Note: These protocols are from animal research and have not been validated for human use

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Then, they should spread their pointer and middle fingers into a "V" and administer the injection between those fingers

Muscle Tissue Preservation: Investigating the muscle-sparing effects of NNMT inhibition during periods of significant fat oxidation