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18 , 33 A study of 37 patients with schizophrenia receiving VPA showed hyperammonaemia in 30% of patients, with the majority of the patients having therapeutic serum VPA concentrations

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described the correlation between serum and CSF UA levels in patients with AD regarding BBB integrity and AD progression [195]

This modification was confirmed through immunoblotting and isotope labeling experiments, demonstrating that it originates from intracellular glycolysis [3]