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The alterable adsorption of enzyme to the interface (EE*) happens in the first equilibrium phase, a single substrate molecule (S) binds by the adsorbed enzyme (E*) in the formation of (E*S) complex as a result in the second phase of equilibrium [74, 75]

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J Allergy Clin Immunol 140(1):109120 Juern AM, Glick ZR, Drolet BA, Frieden IJ (2010) Nevus simplex: a reconsideration of nomenclature, sites of involvement, and disease associations