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Uneven skin tone , aiming for a smoother, more uniform complexion

The holes on the lower section allow the entry of the central vertical rod of the water maze

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I later learned that this is referred to as the heterodimer model: While I still use a graphic like this occasionally in slides when I am introducing the concept of autocatalytic post-translational conformational change to people who arent familiar with it, I think most prion scientists agree this isnt really what goes on