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As for the different sex-related activities of metabolizing enzymes, the specific activity of the catabolic enzyme gamma-glutamyltranspeptidase in female mice was 73% of that in male mice, suggesting that the faster glutathione turnover in males could account for the higher susceptibility to oxidative injury [64]

Meanwhile, eight antioxidant-related genes were found to up-regulate with varying degrees under H 2 O 2 challenge

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