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In comparison, WT cells showed only minor, temperaturedependent changes in fatty acid composition caused by homeoviscous adaptation towards increased SFA content at higher temperatures (Fig 1E and Appendix Fig S2C)

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However, others are less clear (i.e., the negative association of ceramide species with fish intake), highlighting the need for future studies involving stable-isotope feeding trials, lipid-tracer studies, and functional studies in cell and animal models to map the metabolic pathways involved

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