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Phase I safety studies report good tolerability with no serious adverse events at tested doses [9]

Contact your healthcare provider if you experience: Heavy bleeding that soaks through pads or tampons Bleeding that persists beyond six months after starting HRT Bleeding after months of no symptoms Bleeding after sexual intercourse Severe pelvic pain Bleeding that becomes progressively worse Any new bleeding after established menopause These symptoms do not automatically indicate a serious condition, but they should be properly evaluated

doi: 10.3390/nu15122688

The corresponding cysteine in ATPS of the diatom Phaeodactylum tricornutum has been described to be sensitive to oxidation by H 2 O 2 , as well as several other less conserved cysteine residues (Rosenwasser et al., 2014)