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cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis
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The treatment of leukemic cells with curcumin increased intracellular ROS levels, and an additional treatment with the strong antioxidant, glutathione (GSH), and the overexpression of curcumin-binding enzymes partially reversed the effects of curcumin
However, depending on the total administered vector dose, inflammatory reactions may still occur, regardless of the delivery method
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