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Most current studies rely on 16S rRNA-based relative abundance data to describe correlations, with some reporting functional evidence from metabolic products in the uterine that may influence fertility 107,108,109,110

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612 Intriguingly, the study revealed that zinc influx via Zip5 induced Glut2 expression through the activation of Sirt1-mediated Pgc-1, proposing Zip5 as potential therapeutic target for diabetes-related diseases