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Thus, although NHR-80 and NHR-49 are thought to dimerize to regulate fatty acid desaturation (Pathare et al., 2012), they may also have non-overlapping functions

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Also, it has been reported that cholesterol levels could be modulated either by variations of IL28B, ApoE, and LDLR host genes or by dietary components.29 Thus, cholesterol modifications may provide a plausible biochemical tool for making treatment decisions, improving treatment response and favoring viral clearance