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His research highlights three key tissues as fundamental components in mammalian aging and longevity regulation: the hypothalamus (serving as the central control hub), skeletal muscle (functioning as an effector), and adipose tissue (acting as a modulator)

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Moreover, evaluating multiple components within a single research material may help laboratories streamline comparative investigations and analytical review processes

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[11] reported that NNMT knockdown improves glucose tolerance and insulin sensitivity in diet-induced obese mice