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3.2 Phytochelatin synthase-involving pathway engineering for enhancing heavy metal accumulation Pathway engineering involved in the co-expression of both GSH synthesis and PC synthesis pathways is another strategy to preserve the balance of GSH metabolism in the cells with constitutive PC synthesis [72, 74]

Shelton MD

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Figures Abstract Background Glutathione is considered essential for survival in mammalian cells and yeast but not in prokaryotic cells

Homocysteine is then directed through the transsulfuration pathway: homocysteine cystathionine (enzyme: CBS, requires B6) cysteine (enzyme: CSE, requires B6 again)