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Clinics Colon Rectal Surg (2009) 22:1917

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Also, it should be noted that the release of interleukin (IL)-6, a central mediator of inflammation, can be induced by ROS [176, 177]

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The GSH/GPX4 node is the crucial regulator of ferroptosis The GSH system, as a lipid peroxide scavenger, has attracted much attention as a potential therapeutic target for ferroptosis

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Besides this, alpha-synuclein aggregates can spread from cell to cell, which may propagate pathology throughout the brain in a prion-like fashion

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