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(1990) Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity

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Dose reduction is the most underutilised mitigation tool

At 10 mg/mL, every weekly dose in this protocol fits within a single U-100 syringe (100 units) and is drawn from one vial no splitting required
To this date, the only medically recognized use of NAC in increasing cellular glutathione is in acetaminophen poisoning