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More significant increases were observed at the 3- and 6-month marks

A review of B vitamins and one-carbon metabolism highlights the importance of vitamin B12 and folate in the methylation cycle to generate methyl groups for use in DNA synthesis, amino acid homeostasis, antioxidant generation, and epigenetic regulation

Pflaum, M., & Ruman, R

With arthritis, this substance is largely deficient, leading to worsening of the condition

[DOI] [PMC free article] [PubMed] [Google Scholar] 144.Singletary K.W., Rokusek J.T
