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Treatment was administered daily over two days and then the mice were followed for a survival study, where mice were euthanized when tumours reached 2 cm
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Scientific evidence regarding skin-lightening effects remains limited, so realistic expectations and medical guidance are important
These studies suggest that ROS generated during ferroptosis can activate various signaling pathways, such as AMPK, Nrf2, and MAPK, which in turn activate autophagy as a protective mechanism against ferroptosis-induced cell death
