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For example, using structure-based design it might be possible to improve E2E1-I53-50A by optimizing the cleavage site between E2 and E1 and by shortening the linker between the E2E1 and I53-50A moieties, The E2E1-NP immunogens elicited an immediate and strong Ab response against the HVR1 on E2

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10.3171/jns.1994.80.2.0291 J

The PDHB gene is located on chromosome 3p14.3 and is composed of 9 exons that generate three alternatively spliced mRNAs, each of which encodes a distinct protein isoform