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Typical Protocol: Subcutaneous injection daily or several times weekly, often injected near the injury site or systemically

Similar, metabolic disturbances are observed after genetic deletion of the gene coding for the aromatase enzyme (ArKO) in both sexes

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13 A strong inverse correlation has been observed between an animals ability to endogenously produce vitamin C and that animals cortisol response

Many patients have successfully learnt to self-administer B 12 by intramuscular injection, which reduces both healthcare costs and burden on GP practices, and allows people who are B 12 deficient to optimise their treatment regimen.6566 Case example A man in his 70s presents with a nine month history of difficulty walking and climbing stairs, numbness and pain in his lower limbs, and paraesthesia in his hands