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This poses significant challenges for the long-term success of gene therapy, mainly in patients receiving low doses of AAV, such as children, as tissue growth and proliferation may dilute the vector genome, potentially worsening symptoms over time

This daily protocol was maintained for 7 consecutive days, after which cognitive testing demonstrated significant improvements in Morris water maze performance compared to vehicle controls

10.1016/j.tins.2009.08.002 Trends Neurosci

King, D

Simple measures that help many people immediately include staying hydrated, trying small sips of water during episodes, practicing gentle swallowing techniques, avoiding throat clearing, and using a humidifier to reduce throat dryness