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Description
It protects cells from oxidative stress, ensuring they operate efficiently

3.1.2 Effect of sitagliptin on the mRNA expression of BAX, BCL2 and p53 in HepG2 cells Figure 2 illustrates a significant reduction in BCL2 expression level was reported upon treatment of HepG2 cells with the standard anticancer drug doxorubicin in a concentration of 200 mole or with sitagliptin (IC50: 89 M

Yuan L, Lin H, Jiang KJ, Jiao HC, Song ZG

Hepatocyte damage is the basis of abnormal liver function tests (LFTs) in individuals with the GPR120 270H mutation

These mechanisms complement the dopaminergic pathway and address upstream pathogenic processes
