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Taking L-Carnitine in the morning can also be effective, especially if you prefer to take your supplement first thing

doi: 10.4239/wjd.v6.i14.1259 168 MaieseKChongZZShangYCHouJ

While L-Carnitine effectively enhances fatty acid oxidation, its impact on weight loss is relatively modest when used alone

Apart from its participation in fat metabolism, the action of L-carnitine also includes: providing acetyl groups for the production of the neurotransmitter acetylcholine, reducing the production of lactic acid, thereby increasing the ability of muscles to perform, metabolism of branched-chain amino acids (BCAA), carbohydrate metabolism - high levels of L-carnitine in muscles reduce the use of glycogen as an energy material (and increase the use of fat), which is particularly important during prolonged exercise, and inhibits the formation of fat tissue, antioxidant activity, chelating certain metal ions, facilitating their transport and removal of harmful excess from the body

In contrast, the transport of glycolytic substrates such as lactate from oligodendrocytes to neurons is found to be disrupted in SOD1 G93A mice spinal cord (Lee et al., 2012