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DMF treatment decreased the level of L2HG, but not that of D2HG (Fig

Lipid peroxidation scavengers/chain reaction blockers act as radical-trapping antioxidants (RTAs), interrupting the chain amplification of lipid peroxidation and protecting membrane phospholipids, particularly PUFA-containing phospholipids, from oxidative damage

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The pathological hallmarks of PD include the misfolding and aggregation of -syn into LBs, leading to the degeneration of dopaminergic neurons in the substantia nigra pars compacta and the depletion of striatal dopamine

for example, disease free progression of breast cancer is not significantly increased when bevacizumab is delivered with other first line chemotherapeutics (240, 241, 243, 244)