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We then further explored the sharing and specificity of regulation between genes and microbiome via a hierarchical clustering analysis, and noted four gene sets in the transverse colon that show clustering patterns, where genes in set 4 can broadly regulate nearly all families of the microbiome, and genes in set 1 to 3 can each regulate a specific cluster of families (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] Granneman JG, Li P, Zhu Z, Lu Y

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