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Description
When researchers ran GHK data through the Broad Institutes gene-expression maps, the molecule looked like it shifted the activity of several thousand human genes, on the order of a third of the protein-coding genome in that reference set

This triple mechanism distinguishes it from dual-agonist peptides like tirzepatide (GLP-1/GIP) and single-agonist compounds like semaglutide (GLP-1 only), making it the most broadly acting incretin-class compound currently under clinical investigation

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Governments effort to save lives, prevent HIV infections, and accelerate progress toward achieving HIV/AIDS epidemic control in more than 40 countries around the world

[DOI] [PMC free article] [PubMed] [Google Scholar] 76
