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For Leigh syndrome due to SQOR genetic defects, reducing endogenous H 2 S production has proven beneficial: for example, oral metronidazole (to eliminate H 2 S-producing gut microbes) or a low-sulfur diet reversed neuro-metabolic abnormalities in SQOR-deficient mice (Kanemaru et al., 2024)

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Immunogenic cell death (ICD), as a novel antitumor strategy, provides tumor-associated antigens that activate dendritic cells and attract lymphocyte-like T cells into the tumor microenvironment

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10.3389/fpls.2013.00434 65 JayaganeshS.VenkatesanS.SenthurpandianV