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doi: 10.1042/bsr20230374 Pubmed Abstract CrossRef Google Scholar View reference in article 9 PlantoneDPardiniMRinaldiG
[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Ikeda Y., Taniguchi N
Some protocols use two-week escalation intervals with higher starting doses
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These studies generally demonstrate favorable safety profiles, although their therapeutic efficacy is often limited by poor aqueous solubility, rapid metabolism, and low systemic bioavailability
