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It has been proposed that PrfA activation constitutes a two-step process involving initial DNA binding followed by allosteric binding of glutathione for fully transcriptional activation (Reniere et al., 2015)

Knockout of the GST cluster using CRISPR/Cas9 significantly increased the sensitivity of the knockout strain to lambda -cyhalothrin

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Effective sepsis-induced acute lung injury (SALI) therapies remain limited, prompting urgent translational research

Furthermore, alcohol-induced CNS insult results in midline anomalies, such as agenesis of the corpus callosum, also commonly seen in pyruvate dehydrogenase complex deficiency