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Based on studies involving APP/PS1 transgenic mice, FGF-21 has been shown to reduce A plaque deposition and suppress pathological tau hyperphosphorylation in AD model mice by modulating monocarboxylate transporter-dependent metabolic pathways [93]

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For each compound transition 1 (marked in bold) was used for quantification (CE - collision energy, CXP - collision cell exit potential)

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