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Alhallak K, Sun J, Jeske A, et al

In borderline cases, methylmalonic acid or homocysteine levels may be tested

Daratumumab triggers CD38 + multiple myeloma cells [via antibody-dependent cellular cytotoxicity (ADCC), complement dependent cytotoxicity (CDC), and tumor-associated macrophages (TAMs)] in sensitive and drug-resistant patients, regulates the enzyme activity of CD38, reduces the level of adenosine and reduces adenosine-induced immunosuppression
