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Who Should Avoid or Use Caution While Healthletic BPC-157 is designed for broad use across wellness lifestyles, certain groups should approach with added care: Individuals with chronic medical conditions Women who are pregnant or breastfeeding Anyone taking prescription medications, especially for gastrointestinal or autoimmune disorders Its best to have a conversation with your doctor if you fall into any of these categories before beginning a peptide supplement

OSullivan et al 2014)

Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway

This suggests BPC-157 modulates the angiogenic response through pathway interactions rather than acting as a direct angiogenic factor