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SCFAs can affect the blood-brain barrier, neurotransmitter levels, and neurotrophic factors, and directly stimulate the vagus nerve to transmit to the nerves, affecting gut-brain communication (Powley et al., 2019)

Confocal laser scanning microscopy imaging Cells were plated into a confocal petri dish and incubated in a cell incubator (37 C, 5% CO 2 ), and the concentration of LAAM GSH-CQDs was 20 g mL 1

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Barnes PJ, Adcock IM, Ito K (2005) Histone acetylation and deacetylation: importance in inflammatory lung diseases

Studied / plausible use-cases (stronger preclinical support): neuroprotection in ischemia models, neurotrophin modulation (e.g., BDNF), immune/inflammation gene expression changes in stroke models