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Cell Line: 22Rv1 cells Concentration: 0.1 M, 0.5 M, 1 M, 10 M Incubation Time: 6 hours Result: Significant reduction of downstream phosphorylation of RNA Pol II at Ser2 and Ser7, and diminished phosphorylation at Ser5

Science 307 , 538544 (2005)

Major organs, including the heart, liver, spleen, lung, and kidneys, were collected for histological analysis

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Phenotypic and functional heterogeneity of cancer-associated fibroblast within the tumor microenvironment