concentration of glutathione in plasma species and their ratio from the The Biological Functions of Glutathione

Several allyl sulfides, namely, diallyl sulfide (DAS), diallyl disulfide (DADS), and diallyl trisulfide (DATS) are major components of garlic that are capable of inducing phase II detoxification enzymes in a Nrf2-dependent manner [203, 204, 219]

That doesnt mean low glutathione is the sole cause of fatigue, but it does play a role in how the body handles physical and environmental stressors

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Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]

minimize oxygen and headspace