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Another extracellular mechanism for triggering cell death involves the interaction of receptors and ligands, such as the Fas/FasL system, which can also initiate apoptotic events under certain conditions (Yamada et al., 2017)

World Journal of Gastroenterology, 24(47), 53665378

Additionally, multiple immune-related pathways were activated via lipid peroxidation, such as TLR4, AGER and STING1 pathways (Fig

doi: 10.1038/emboj.2011.105

Reversible covalent inhibitor GC376 was used as a positive control, which will not be removed by buffer exchange after covalent binding to 3CL
