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Among transfusion-dependent patients with hemoglobinopathies, the ototoxicity incidence with deferoxamine (DFO) at doses below 50 mg/kg/day was 27%, whereas deferiprone and deferasirox were not associated with recognized ototoxicity
Amara, N
A 2025 systematic review found no meaningful clinical safety data and only very low-level human studies, including a small retrospective report in knee pain [12]
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doi: 10.1152/ajprenal.00567.2019, 213
