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Recent trends in intervertebral disc degeneration research reveal three key developments: minimally invasive techniques, particularly robotic-assisted and endoscopic surgeries, have become the predominant surgical approach

Antibodies against T-cell immunological negative regulators (PD1, PDL1, and CTLA4) directly boost the immune system, resulting in extraordinary clinical success in a range of malignancies and FDA approval of the following immune checkpoint targeted immunotherapies [109]

Others use injections as a targeted boost during stressful times or health slumps

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They are instrumental in studying the cellular and molecular responses to SCI