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Similarly, conditional knockout mice lacking Cacna1c in the cerebral cortex, which encodes the L-type, voltage-dependent, Ca 2+ -channel, alpha 1 C subunit that is among the most commonly identified risk genes for bipolar disorder, have reduced spontaneous cortical Ca 2+ activity and display hyperactive, manic-like behaviour [27, 28]

Oxidation of polyunsaturated fatty acids and lipids through thiyl and sulfonyl radicals: Reaction kinetics, and influence of oxygen and structure of thiyl radicals

Abstract The brain is a highly complex, multicellular organ composed of diverse neuronal and nonneuronal cell types that function in concert to maintain central nervous system homeostasis
