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Description
the antibody or ADC of embodiment 37 wherein the antibody or ADC further comprises a VL CDR3 having an amino acid sequence of a VL CDR3 of 12G3H11, B233, B208, B210, G5, 10C12, 4H5, 10G9, 3F2, 1C1, 1F12, 1H3, 1D3, 2B12, or 5A8
Besides, a recent study showed that UA could synergically inhibit Akt/mTOR and TNF-/TNFR1 signaling pathways, and promote autophagy, thereby inhibiting the pyroptosis and necroptosis of macrophages induced by Mtb , and enhancing the intracellular killing of Mtb (Shen et al., 2023)
10.1093/ibd/izaf006 103
Assists the liver in neutralizing harmful toxins
Health A
