Ferroptosis: process and function
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Typically, Fe 3+ is internalized and carried to endosomes by means of the transferrin receptor (Kawabata, 2019)
[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Bourgeron T
Thus, deletion or inhibition of Lp-PLA2 results in the accumulation of PE species, including PE(38:4), facilitating ferroptosis 70
In other experimental conditions, long-term exposure of the cells and animals to hyperglycemic conditions could develop insulin resistance, which leads to excess production of ROS (Afanasev, 2010
J.Bierma-ZeinstraS
