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A patch may have a white center surrounded by paler skin

I know this is a result of the vaccine, and may be part of the immune response, but no one can confirm that for me

Biochem Biophys Res Commun 1999;258:722726

7E (left panels) and Supplementary Fig
Adults over 50 are more likely to develop B12 deficiency without realizing it, especially if symptoms like fatigue, memory loss, or mood changes are attributed to aging itself