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Description
ERS can activate the expression of Ca 2+ release channels on inositol 1,4,5-trisphosphate receptors (IP3R), thereby mediating the release of ER-Ca 2+

4 and Supplementary Table 13)

[DOI] [PubMed] [Google Scholar] 26.Hartl D, Starosta V, Maier K, Beck-Speier I, Rebhan C, Becker BF, et al

In immune cells or stressed tissues, this dysfunction triggers immunometabolic reprogramming

IRE1, inositol requiring enzyme-1
