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[DOI] [PubMed] [Google Scholar] 114.Pereira-Caro G., Madrona A., Bravo L., Espartero J.L., Alcudia F., Cert A., Mateos R

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Linus Pauling Institute

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81,82 Aging also promotes the proinflammatory polarization of monocytes by increasing the plasma saturated fatty acid concentration, thereby increasing the production of IL-6 and TNF- but inhibiting the production of IL-10 and transforming growth factor- (TGF-1)

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19,84 Hepatocyte-specific SIRT1 knockout mice display liver steatosis, triglyceride accumulation, and increased de novo lipogenesis, even under standard dietary conditions, accompanied by SREBP-1c activation and impaired PGC-1/peroxisome proliferator-activated receptor alpha (PPAR) signaling

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