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*Correspondence: Anwen Shao, [email protected]

Oral administration does not produce a measurable plasma half life because the compound never reaches systemic circulation in sufficient quantities

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

NAD + levels are limiting in this reaction and determine the efficiency of mitochondrial energy production 15

Many payers also require step therapy documentation (proof the patient tried lower-cost alternatives)
