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Description
initially identified histone lactylation in 2019, proposing it as a novel form of epigenetic regulation that preliminarily connected lactate metabolism to transcriptional control [15]

Treatment with GLY reduced the levels of ROS, MDA and LDH

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In fact, the gene encoding the catalytic subunit of GCL ( GCLC ) is under the control of the antioxidant-responsive element (ARE), promoting the binding of the major detoxification-involved transcription factor (TF), nuclear factor erythroid 2-related factor 2 (Nrf2) [20]

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