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Description
Nat Prec (2012)

Citrate-derived acetyl-CoA is used as a precursor for lipid biosynthesis and protein acetylation

Additionally, various difficult toxicities associated with MTX such as testicular toxicity, which is regarded as a severe adverse effect that may result in infertility, may limit the drugs therapeutic impact (Howard et al

Dhaliwal, J

These data have highlighted a number of key data and knowledge gaps, which hopefully will be addressed in the future
