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Many independent studies show the elevated levels of MDA, F2-Isoprostane, nitric oxide and diminished levels of reduced glutathione in patients with lupus nephritis [1417]

At the cellular level, vitamin B12 is involved in DNA synthesis and neuroprotection, acting as a cofactor for enzymes critical to these processes, such as methionine synthase and methylmalonyl-CoA mutase (, )

Woodruff, P

Tao W, Liu F, Zhang J, Fu S, Zhan H, Qian K

These finding imply that targeting MAMs may hold promise as a therapeutic approach for the treatment of neuroinflammatory diseases
