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Disadvantages: Cannot penetrate deeply into the skin Cannot create systemic effects like the capsule and tablet forms Works slowly and takes time to produce effects Topical Glutathione is often consumed alongside oral and skincare products

Clinical experience strongly supports its use for the indications below but we're working with promising preclinical data, not robust human RCTs

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What rodent data can't tell us: species-specific differences in NNMT expression and NAD+ salvage pathways mean rats may tolerate prolonged NNMT inhibition differently than humans