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Epidemiological evidence further substantiates the independent association between elevated levels of BCAAs and the incidence of CHD, as well as its prevalent traditional risk factors, including insulin resistance, dyslipidemia and endothelial dysfunction

Atherosis means fat accumulation goes along with several macrophages, and sclerosis is defined as a fibrosis layer consisting of smooth muscle cells, connective tissues, and leukocytes (46)

Iuliano S, Poon S, Robbins J, et al

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